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Immediate allergy to natural latex: clinical and immunological studies.

作者信息

Losada E, Lázaro M, Marcos C, Quirce S, Fraj J, Dávila I, Igea J M, Sánchez-Cano M

机构信息

Servicio de Alergia, Hospital Ramón Y Cajal, Madrid, Spain.

出版信息

Allergy Proc. 1992 May-Jun;13(3):115-20. doi: 10.2500/108854192778878773.

DOI:10.2500/108854192778878773
PMID:1387097
Abstract

Since 1979 several reports of contact urticaria due to natural latex have been documented. In recent years cases of anaphylaxis, rhinitis, and asthma due to latex have appeared. Nine patients, studied in our clinic between 1986-1991, suffered immediate allergic reactions caused by rubber products. All showed an immediate skin reaction to latex extract. Rub testing with surgical gloves was positive in eight patients. Immunological techniques (RAST, ELISA, HRT) demonstrated specific IgE against latex. Specific bronchial provocation testing was performed in one patient who presented with asthma when she used latex surgical gloves. Patch testing to common rubber additives were negative in our patients. These results suggest that natural latex antigens present in rubber objects can cause hypersensitivity reactions probably due to IgE-mediated mechanisms.

摘要

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