Messerli F H, Soria F
Department of Internal Medicine, Ochsner Clinic, New Orleans, Louisiana 70121.
Am J Med. 1992 Aug 31;93(2A):21S-26S. doi: 10.1016/0002-9343(92)90291-i.
Left ventricular hypertrophy (LVH) is a common sequela of sustained arterial hypertension, although the correlation between spot blood pressure measurements and LV mass is not a close one. LVH has been shown to be a powerful blood pressure-independent risk factor for cardiovascular morbidity and mortality. LVH has been shown to trigger or to accelerate ventricular dysrhythmias, although the connection between ventricular dysrhythmias and sudden death is poorly documented. LVH can be reduced by specific antihypertensive therapy; however, not all drugs are equipotent in this regard. A reduction of LVH has been shown to be associated with a suppression of ventricular dysrythmias. Preliminary studies also indicate that the reduction of LVH may reduce its inherent excessive morbidity and mortality.
左心室肥厚（LVH）是持续性动脉高血压的常见后遗症，尽管单次血压测量值与左心室质量之间的相关性并不紧密。LVH已被证明是心血管发病和死亡的一个强大的血压非依赖性危险因素。LVH已被证明可引发或加速室性心律失常，尽管室性心律失常与猝死之间的联系记录较少。特定的抗高血压治疗可减轻LVH；然而，并非所有药物在这方面都具有同等效力。已证明减轻LVH与抑制室性心律失常有关。初步研究还表明，减轻LVH可能会降低其固有的过高发病率和死亡率。
