Artacho-Pérula E, Roldán-Villalobos R, Roldán-Villalobos A, Salas-Molina J, Vaamonde-Lemos R
Department of Morphological Sciences, School of Medicine, University of Córdoba, Spain.
Anal Quant Cytol Histol. 1992 Aug;14(4):320-9.
The authors dated 100 normal endometrial biopsies. Only endometrial specimens with histologically confirmed subphases and no evidence of organic disease were accepted for study. The morphometry and stereologic measures of the glands, lumina and endometrial epithelium were assessed. Quantitative assessment of the normal endometrium supported the histologic events that occur in the endometrial cycle (proliferative and secretory phases). There was a progressive increase in morphometric and stereologic values of the glands, epithelium and lumina during the endometrial cycle. Using stepwise discriminant analysis, 94% of the specimens were correctly classified into the categories of proliferative and secretory phase; two quantitative parameters were required, the epithelial volume density and longest luminal diameter. When three subphases within proliferative and secretory endometrium were considered, the overall accuracy was 90% and 78%, respectively.
作者对100份正常子宫内膜活检样本进行了分期。仅接受组织学确诊为亚期且无器质性疾病证据的子宫内膜样本用于研究。对腺体、管腔和子宫内膜上皮的形态计量学和体视学指标进行了评估。对正常子宫内膜的定量评估支持了子宫内膜周期（增殖期和分泌期）中发生的组织学事件。在子宫内膜周期中，腺体、上皮和管腔的形态计量学和体视学值逐渐增加。使用逐步判别分析，94%的样本被正确分类为增殖期和分泌期；需要两个定量参数，即上皮体积密度和管腔最长直径。当考虑增殖期和分泌期子宫内膜内的三个亚期时，总体准确率分别为90%和78%。
