Bonfils P, Avan P
Otorhinolaryngology Department, Hôpital Boucicaut, Paris, France.
Arch Otolaryngol Head Neck Surg. 1992 Oct;118(10):1069-76. doi: 10.1001/archotol.1992.01880100061014.
Distortion-product otoacoustic emissions are otoacoustic emissions evoked by two pure tones. They are proposed as a frequency-specific test of the mechanical properties of the cochlea. The aim of this study was to measure distortion-product otoacoustic emissions in a clinical setting to establish the most interesting values suitable for clinical use and the clinical interest of the method. The statistical analysis of the data points out some clinically interesting values: (1) a screening limit value of 30 dB hearing level and when measuring distortion-product otoacoustic emissions in response to 52 dB sound pressure level for studying active frequency selective mechanisms; (2) a screening limit value of 50 dB hearing level and when measuring distortion-product otoacoustic emissions in response to 72 dB sound pressure level for studying passive cochlear mechanisms; and (3) the slope of the input-output function. All physiologic properties of the cochlea fit with these basic distortion-product otoacoustic emission properties. These criteria can be used whatever the population studied and the material used for distortion-product otoacoustic emissions recordings. Distortion-product otoacoustic emissions can be used as a screening test to separate (1) subjects with normal hearing and subjects with a hearing threshold above 30 dB hearing level (distortion-product otoacoustic emissions in response to a 52 dB sound pressure level "primaries" [ie, pure tones] stimulation intensity), and (2) patients with a hearing threshold above or below 50 dB hearing level (distortion-product otoacoustic emissions in response to a 72 dB sound pressure level primary stimulation intensity). Distortion-product otoacoustic emissions cannot be used as a more precise audiometric test.
畸变产物耳声发射是由两个纯音诱发的耳声发射。它们被提议作为一种针对耳蜗机械特性的频率特异性测试。本研究的目的是在临床环境中测量畸变产物耳声发射，以确定最适合临床使用的有趣数值以及该方法的临床价值。对数据的统计分析指出了一些具有临床意义的数值：（1）听力级30 dB的筛查限值，以及在测量对52 dB声压级做出反应的畸变产物耳声发射时，用于研究主动频率选择机制；（2）听力级50 dB的筛查限值，以及在测量对72 dB声压级做出反应的畸变产物耳声发射时，用于研究耳蜗被动机制；（3）输入-输出函数的斜率。耳蜗的所有生理特性都与这些基本的畸变产物耳声发射特性相符。无论所研究的人群以及用于记录畸变产物耳声发射的材料如何，这些标准都可以使用。畸变产物耳声发射可用作一种筛查测试，以区分（1）听力正常的受试者和听力阈值高于听力级30 dB的受试者（对52 dB声压级“原刺激音”[即纯音]刺激强度做出反应的畸变产物耳声发射），以及（2）听力阈值高于或低于听力级50 dB的患者（对72 dB声压级原刺激强度做出反应的畸变产物耳声发射）。畸变产物耳声发射不能用作更精确的听力测试。
