Serra Lucieny, Novanta Gabriela, Sampaio Andre Lopes, Augusto Oliveira Carlos, Granjeiro Ronaldo, Braga Silvia Cristina
Department of Otolaryngology, Universidade de Brasília, Brasília, Distrito Federal, Brazil.
Secretaria de Saúde-Hospital de Base, Brasília, Distrito Federal, Brazil.
Int Arch Otorhinolaryngol. 2015 Apr;19(2):171-5. doi: 10.1055/s-0034-1374648. Epub 2014 Jun 18.
Introduction Analysis of the suppression effect is a simple method to evaluate cochlear status and central auditory mechanisms and, more specifically, the medial olivocochlear system. This structure may be involved in the generation of mechanisms that cause tinnitus and in the pathophysiology of tinnitus in patients with tinnitus and normal hearing. Objective To review the literature of the etiology of tinnitus on the lights of otoacoustic emissions in patients with normal hearing. Data Synthesis Individuals with tinnitus and normal hearing have a higher prevalence of alterations in transient-evoked otoacoustic emissions and distortion-product otoacoustic emissions than normal subjects. This fact suggests that dysfunctions of the outer hair cells (OHCs) might be important in the generation of the tinnitus; however, this feature is not always present in those who have the symptoms of tinnitus. Final Comments These findings suggest that OHC dysfunction is not necessary for tinnitus development-that is, there might be mechanisms other than OHC damage in the tinnitus development. On the other hand, OHC dysfunction alone is not sufficient to cause the symptom, because a great many individuals with OHC dysfunction did not complain about tinnitus.
抑制效应分析是评估耳蜗状态和中枢听觉机制，尤其是内侧橄榄耳蜗系统的一种简单方法。该结构可能参与了耳鸣产生机制的形成以及听力正常的耳鸣患者耳鸣的病理生理过程。目的：根据听力正常患者的耳声发射情况综述耳鸣病因的文献。资料综合：耳鸣且听力正常的个体，其瞬态诱发耳声发射和畸变产物耳声发射的改变发生率高于正常受试者。这一事实表明，外毛细胞（OHC）功能障碍可能在耳鸣的产生中起重要作用；然而，有耳鸣症状的患者并非都存在这一特征。总结评论：这些发现表明，OHC功能障碍并非耳鸣发生所必需，也就是说，在耳鸣发生过程中可能存在除OHC损伤之外的其他机制。另一方面，单纯的OHC功能障碍不足以导致该症状，因为许多OHC功能障碍的个体并未诉说有耳鸣症状。
