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由于精细结构导致在客观听力测定中使用畸变产物耳声发射的局限性。

Limitations in the use of distortion product otoacoustic emissions in objective audiometry as the result of fine structure.

作者信息

Heitmann J, Waldmann B, Plinkert P K

机构信息

Universität Tübingen, Lehrstuhl für Tierphysiologie, Germany.

出版信息

Eur Arch Otorhinolaryngol. 1996;253(3):167-71. doi: 10.1007/BF00615115.

Abstract

There is strong evidence for a link between intact cochlear function and otoacoustic emissions (OAE). However, all attempts to find a close correlation between auditory thresholds and amplitudes of distortion product otoacoustic emissions (DPOAE) have failed. As an explanation for these findings, we have studied DPOAE fine structure and its dependence on increasing primary sound levels. Errors due to different calibrations of equipment for measuring DPOAE and auditory thresholds were also investigated. DPOAE were measured in 16 subjects using a frequency range of 500-1000 Hz. Frequencies were changed in 12.5 Hz steps at primary levels of 55, 60, 65 and 70 dB SPL. DPOAE amplitudes were found to vary by up to 20 dB for a frequency step of 50 Hz. Some fine structures showed narrow dips that shifted in frequency and diminished in amplitude with increasing primary levels. These findings demonstrated that sampling DPOAE amplitudes at widely spaced frequencies gave incomplete information about true course. DPOAE growth functions measured close to a dip in the DPOAE fine structure were rendered useless by interference with either the frequency shift or amplitude variations of the dip at different primary levels.

摘要

有充分证据表明完整的耳蜗功能与耳声发射(OAE)之间存在联系。然而,所有试图找到听觉阈值与畸变产物耳声发射(DPOAE)幅度之间紧密相关性的尝试均告失败。作为对这些发现的解释,我们研究了DPOAE的精细结构及其对初级声级增加的依赖性。还研究了由于测量DPOAE和听觉阈值的设备校准不同而导致的误差。使用500 - 1000 Hz的频率范围对16名受试者进行了DPOAE测量。在55、60、65和70 dB SPL的初级声级下,频率以12.5 Hz的步长变化。发现对于50 Hz的频率步长,DPOAE幅度变化高达20 dB。一些精细结构显示出狭窄的凹陷,其频率会发生偏移,并且随着初级声级的增加幅度会减小。这些发现表明,在间隔较大的频率上采样DPOAE幅度会得到关于真实变化过程的不完整信息。在接近DPOAE精细结构凹陷处测量的DPOAE增长函数,由于在不同初级声级下受到凹陷的频率偏移或幅度变化的干扰而变得无用。

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