Tovi M, Ericsson A
Department of Diagnostic Radiology, Akademiska Sjukhuset, Uppsala University, Sweden.
Acta Radiol. 1992 Sep;33(5):400-4.
T1 and T2 were measured in 5 formalin-fixed human whole-brain specimens as a function of time. Gray matter/white matter contrast reversal was observed around the 4th day and was considered to be due to the greater decrease in T1 in gray than in white matter. A possible explanation for this is that the decomposition of the myelin phospholipid structure by formalin somewhat counteracts the general reductive effect of the fixation procedure on relaxation times.
在5个经福尔马林固定的人类全脑标本中，测量了T1和T2随时间的变化。在第4天左右观察到灰质/白质对比度反转，这被认为是由于灰质中T1的下降幅度大于白质。对此的一种可能解释是，福尔马林对髓磷脂磷脂结构的分解在一定程度上抵消了固定过程对弛豫时间的一般还原作用。
