干扰素在痘苗病毒感染小鼠胚胎组织培养中的作用。
The role of interferon in vaccinia virus infection of mouse embryo tissue culture.
作者信息
GLASGOW L A, HABEL K
出版信息
J Exp Med. 1962 Mar 1;115(3):503-12. doi: 10.1084/jem.115.3.503.
Abstract
The production of an interferon-like substance by vaccinia virus is described. The physical properties of vaccinia interferon are shown to be similar to those of previously reported interferons. Data defining the role of vaccinia interferon in cell resistance and in establishment and maintenance of a carrier culture are presented. Elimination of virus from an infected culture is demonstrated and the role of interferon in the recovery process is considered.
摘要
本文描述了痘苗病毒产生一种类干扰素物质的情况。痘苗干扰素的物理特性显示与先前报道的干扰素相似。文中给出了确定痘苗干扰素在细胞抗性以及在载体培养的建立和维持中作用的数据。证明了从受感染培养物中清除病毒，并探讨了干扰素在恢复过程中的作用。
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Further studies on an inhibitor of viral activity appearing in infected cell cultures and its role in chronic viral infections.关于感染细胞培养物中出现的病毒活性抑制剂及其在慢性病毒感染中作用的进一步研究。
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