Raguin G, Boisnic S, Souteyrand P, Baranton G, Piette J C, Godeau P, Francès C
Department of Internal Medicine, Hôpital Pitié-Salpêtrière, Paris, France.
Br J Dermatol. 1992 Sep;127(3):218-20. doi: 10.1111/j.1365-2133.1992.tb00117.x.
We looked for evidence of a Borrelia infection in 15 patients with morphoea. We were not able to detect antibodies to Borrelia burgdorferi in any of these 15 patients. None of the 14 skin biopsies examined by immunohistochemistry showed evidence of spirochaetes. Skin biopsies were cultured in 10 patients. All were negative. These results do not support a spirochaetal origin of localized scleroderma.
我们在15例硬斑病患者中寻找伯氏疏螺旋体感染的证据。在这15例患者中，我们均未能检测到抗伯氏疏螺旋体的抗体。经免疫组织化学检查的14份皮肤活检标本均未显示螺旋体的证据。10例患者的皮肤活检标本进行了培养，结果均为阴性。这些结果不支持局限性硬皮病的螺旋体起源。
