毛细胞白血病中的组织胞浆菌病：病例报告及文献复习

Histoplasmosis in hairy cell leukemia: case report and review of the literature.

作者信息

Weeks E, Jones C M, Guinee V, Shallenberger R, Sarosi G A, Bunnell P A

机构信息

Division of Hematology, University of Texas Medical School, Houston.

出版信息

Ann Hematol. 1992 Sep;65(3):138-42. doi: 10.1007/BF01695814.

DOI:10.1007/BF01695814

PMID:1391124

Abstract

Progressive disseminated histoplasmosis (PDH) has been described in only six patients with hairy cell leukemia (HCL). Herein we describe an additional patient with HCL and disseminated histoplasmosis. Additionally, we note that three of seven cases of disseminated histoplasmosis and HCL have occurred in East Texas. PDH is to be suspected in febrile HCL patients in an endemic area who fail to respond to antibacterial therapy. We emphasize that serologic studies are useful in the diagnosis of PDH in HCL patients, and these patients respond well to therapy.

摘要

进展性播散性组织胞浆菌病（PDH）仅在6例毛细胞白血病（HCL）患者中被描述过。在此，我们描述了另外1例患有HCL和播散性组织胞浆菌病的患者。此外，我们注意到，7例播散性组织胞浆菌病和HCL病例中有3例发生在东得克萨斯州。对于流行地区发热且对抗菌治疗无反应的HCL患者，应怀疑患有PDH。我们强调，血清学研究对HCL患者PDH的诊断有用，并且这些患者对治疗反应良好。