Oshio K, Mulkern R V
Department of Radiology, Brigham and Women's Hospital, Boston, MA.
J Magn Reson Imaging. 1992 Sep-Oct;2(5):601-4. doi: 10.1002/jmri.1880020521.
An inner-volume modification of a spectroscopic imaging technique based on RARE (rapid acquisition with relaxation enhancement) sequences is shown to provide, in less than 1 minute, spectra suitable for fat/water peak-area integration from selected imaging columns containing more than 1,000 5 x 5 x 1-mm voxels. A limitation is the unavoidable T2 weighting of the spectral peaks, which influences estimations of true fat/water composition from the spectra. Studies obtained in the knees of healthy volunteers demonstrate the ability of the technique to enable characterization of the two major proton peaks in bone marrow. Data collected at two or more effective TEs are suitable for extrapolation of fat/water estimates to zero TE.
基于RARE（弛豫增强快速采集）序列的光谱成像技术的一种内部容积改进方法显示，在不到1分钟的时间内，就能从包含1000多个5×5×1毫米体素的选定成像列中提供适合脂肪/水峰面积积分的光谱。一个局限性是光谱峰不可避免的T2加权，这会影响从光谱中对真实脂肪/水成分的估计。在健康志愿者膝盖上进行的研究证明了该技术能够对骨髓中的两个主要质子峰进行表征。在两个或更多有效回波时间（TE）采集的数据适用于将脂肪/水估计值外推到零TE。
