Hall M E, MacDonald S, Young G C
St. Michael's Hospital, Toronto, Ontario, Canada.
Brain Inj. 1992 Sep-Oct;6(5):435-45. doi: 10.3109/02699059209008139.
In view of the difficulties in finding control groups in sensory stimulation research, a single case methodology was explored. A pilot study was conducted on six comatose CHI patients in a neurosurgical intensive care unit. Each patient was given alternating weeks of directed multisensory stimulation (SDS) and non-directed stimulation (NDS) for half an hour a day in an ABAB single subject design. Eye movement, motor and vocal response to stimulation were recorded using the Sensory Stimulation Assessment Measure (Rader Scale). Comparisons of eye movement and motor responses on the Rader Scale appeared to indicate a greater degree of responsiveness to the SDS as compared with the NDS treatment. Overall improvement levels on the GCS, Rancho Scale and Western Neurosensory Stimulation Profile are discussed. The results are interpreted as indicative of the potential value of using single case methodology in this population, and future research directions are also discussed.
鉴于在感觉刺激研究中难以找到对照组，我们探索了单病例方法。对神经外科重症监护病房的6名昏迷的脑外伤患者进行了一项试点研究。采用ABAB单受试者设计，每位患者交替接受为期一周的定向多感觉刺激（SDS）和非定向刺激（NDS），每天半小时。使用感觉刺激评估量表（雷德量表）记录对刺激的眼球运动、运动和声音反应。雷德量表上眼球运动和运动反应的比较似乎表明，与NDS治疗相比，患者对SDS的反应程度更高。讨论了格拉斯哥昏迷量表（GCS）、兰乔量表和西部神经感觉刺激概况的总体改善水平。结果被解释为表明在这一人群中使用单病例方法的潜在价值，并讨论了未来的研究方向。
