Stanová L, Siman J, Chorváth D, Kanáliková K, Havelová L, Culen M
Rádiodiagnostické oddelenie UKVCH, Bratislava, CSFR.
Bratisl Lek Listy. 1992 May;93(5):250-7.
The studied series consisted of 14 patients with ventricular septal defect and pulmonary hypertension aged from 3 months to 15 years. Three examination methods were compared: (1) Invasive hemodynamic examination; (2) Pulmoangiographic examination by means of wedge peripheral pulmoangiography; (3) Histological examination of bioptic samples. Direct correlation was found to exist between mean PA pressure, PAR/m2, TPR/SR and pulmoangiographic records, in which the following parameters were evaluated: (a) length of the narrowing of the peripheral branch of the PA, (b) background opacity, (c) circulation time. The histological findings obtained in the bioptic samples corresponded practically in all cases with the hemodynamic and PAG findings. Only in two patients did the histological picture display a less severe degree of affection than found by PAG and hemodynamic examination. The obtained results suggest that in light of surgical indications, PAG can be considered a suitable and valuable supplementary method in assessing borderline findings of pulmonary hypertension in children with congenital heart defects and left-to-right shunt.
该研究系列包括14例室间隔缺损合并肺动脉高压的患者,年龄在3个月至15岁之间。比较了三种检查方法:(1)有创血流动力学检查;(2)通过楔形外周肺血管造影进行的肺血管造影检查;(3)活检样本的组织学检查。发现平均肺动脉压、PAR/m2、TPR/SR与肺血管造影记录之间存在直接相关性,其中评估了以下参数:(a)肺动脉外周分支狭窄长度,(b)背景不透明度,(c)循环时间。活检样本的组织学结果在所有病例中实际上都与血流动力学和肺血管造影结果相符。只有两例患者的组织学表现显示出的病变程度比肺血管造影和血流动力学检查发现的要轻。所获得的结果表明,根据手术指征,肺血管造影可被视为评估先天性心脏缺损和左向右分流患儿肺动脉高压临界结果的一种合适且有价值的辅助方法。