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角膜的血清学特异性。

The serological specificity of the cornea.

作者信息

NELKEN D, NELKEN E

出版信息

Immunology. 1962 Sep;5(5):595-602.

PMID:13938009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1424162/
Abstract

Tannic-acid haemagglutination and complement-fixation tests as well as agar-gel precipitation revealed the presence of antigens in the human cornea which are also present in human epidermis, leukocytes and serum. Similar species specific antigens were also observed in rabbit cornea, epidermis, leucocytes and serum. Organ specific antigens were found in human and rabbit cornea. Individual specific corneal antigens in man were rarely observed and only in cases in which anti-corneal serum from patients after keratoplasty operations was used. The importance of corneal antigens in relation to corneal homografting operations is discussed.

摘要

单宁酸血细胞凝集试验、补体结合试验以及琼脂凝胶沉淀试验表明，人角膜中存在的抗原也存在于人体表皮、白细胞和血清中。在兔角膜、表皮、白细胞和血清中也观察到了类似的种属特异性抗原。在人和兔角膜中发现了器官特异性抗原。在人类中，个体特异性角膜抗原很少被观察到，仅在使用角膜移植术后患者的抗角膜血清的情况下出现。本文讨论了角膜抗原与同种异体角膜移植手术的关系。

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SEROLOGICAL STUDIES IN KERATOPLASTY.角膜移植的血清学研究。
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Circulating cornea-specific antibodies in corneal disease and cornea transplantation.
Graefes Arch Clin Exp Ophthalmol. 1994 Feb;232(2):82-6. doi: 10.1007/BF00171668.
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On the significance of the phacoautoantibodies demonstrated in the sera of patients with senile cataract.关于在老年性白内障患者血清中所证实的晶状体蛋白自身抗体的意义
Immunology. 1967 Mar;12(3):321-5.
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Circulating antibodies to corneal tissue in a patient suffering from Mooren's ulcer (ulcus rodens corneae).患有蚕食性角膜溃疡（角膜溃疡性穿孔）患者体内针对角膜组织的循环抗体。
Clin Exp Immunol. 1969 Oct;5(4):365-70.
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Induction of autoantibodies to rat corneal protein 54.诱导针对大鼠角膜蛋白54的自身抗体。
Clin Exp Immunol. 1992 Apr;88(1):101-6. doi: 10.1111/j.1365-2249.1992.tb03046.x.

本文引用的文献

1
Specific antigens of human leucocytes and thrombocytes.人类白细胞和血小板的特异性抗原。
Nature. 1961 Nov 4;192:466-7. doi: 10.1038/192466b0.
2
Corneal antigenicity. Immunoelectrophoretic study.
Arch Ophthalmol. 1960 Sep;64:413-25. doi: 10.1001/archopht.1960.01840010415015.
3
Synergic action between isoantibody and immune cells in graft rejection.
Transplant Bull. 1960 Oct;26:449-53. doi: 10.1097/00006534-196010000-00037.
4
Studies on antigens in the human cornea and their relationship to corneal grafting in man.人体角膜中的抗原及其与人角膜移植关系的研究。
J Lab Clin Med. 1957 May;49(5):745-52.
5
Studies on the immunological response to foreign tumor transplants in the mouse. II. The relation between hemagglutinating antibody and graft resistance in the normal mouse and mice pretreated with tissue preparations.小鼠对外来肿瘤移植的免疫反应研究。II. 正常小鼠及经组织制剂预处理的小鼠中血凝抗体与移植抗性之间的关系。
J Exp Med. 1955 Aug 1;102(2):179-97. doi: 10.1084/jem.102.2.179.

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