Schaap O L, Feltkamp T E, Breebaart A C
Clin Exp Immunol. 1969 Oct;5(4):365-70.
Autoantibodies to human corneal epithelium were demonstrated by the immunofluorescent technique in the serum of a patient suffering from ulcus rodens corneae (Mooren's ulcer). These antibodies were demonstrated in serum obtained before lamellar keratoplasty, and in samples taken 1½ and 4 years, respectively, after operation, when the process had reached the terminal stage. No antibodies fixed were demonstrated in the patient's own corneal tissue using the direct immunofluorescent technique. However, in the serum of three other patients suffering from the same disease no antibodies could be demonstrated. Two of these sera were from patients who had undergone keratoplasty.
采用免疫荧光技术在蚕食性角膜溃疡（莫伦氏溃疡）患者血清中检测到了抗人角膜上皮的自身抗体。这些抗体在板层角膜移植术前采集的血清中得到证实，在术后1.5年和4年病情发展至末期时采集的样本中也得到证实。采用直接免疫荧光技术未在患者自身角膜组织中检测到固定的抗体。然而，在另外三名患有相同疾病的患者血清中未检测到抗体。其中两名患者的血清来自接受过角膜移植术的患者。
