deLemos R, Yoder B, McCurnin D, Kinsella J, Clark R, Null D
Department of Physiology and Medicine, Southwest Foundation for Biomedical Research, San Antonio, Texas 78228.
Early Hum Dev. 1992 Jun-Jul;29(1-3):299-303. doi: 10.1016/0378-3782(92)90181-f.
The use of high-frequency oscillatory ventilation (HFOV) was evaluated as a rescue intervention in 122 consecutive infants meeting criteria for extracorporeal membrane oxygenation (ECMO). Fifty-three percent responded to HFOV and never required ECMO, 3/65 died. Infants who ultimately required ECMO had lower aortic and pulmonary peak flow velocities, and lower pulmonary acceleration, circumferential fiber shortening and shortening fraction than those who were successfully managed with HFOV. The use of HFOV with an appropriate strategy decreased the need for ECMO in this patient population.
