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我们能否改善先天性膈疝的治疗结果?

Can we improve outcome of congenital diaphragmatic hernia?

作者信息

van den Hout L, Sluiter I, Gischler S, De Klein A, Rottier R, Ijsselstijn H, Reiss I, Tibboel D

机构信息

Department of Paediatric Surgery, ErasmusMC-Sophia, Rotterdam, The Netherlands.

出版信息

Pediatr Surg Int. 2009 Sep;25(9):733-43. doi: 10.1007/s00383-009-2425-8.

Abstract

This review gives an overview of the disease spectrum of congenital diaphragmatic hernia (CDH). Etiological factors, prenatal predictors of survival, new treatment strategies and long-term morbidity are described. Early recognition of problems and improvement of treatment strategies in CDH patients may increase survival and prevent secondary morbidity. Multidisciplinary healthcare is necessary to improve healthcare for CDH patients. Absence of international therapy guidelines, lack of evidence of many therapeutic modalities and the relative low number of CDH patients calls for cooperation between centers with an expertise in the treatment of CDH patients. The international CDH Euro-Consortium is an example of such a collaborative network, which enhances exchange of knowledge, future research and development of treatment protocols.

摘要

本综述概述了先天性膈疝(CDH)的疾病谱。描述了病因、生存的产前预测因素、新的治疗策略和长期发病率。早期识别CDH患者的问题并改进治疗策略可能会提高生存率并预防继发性疾病。多学科医疗保健对于改善CDH患者的医疗保健是必要的。缺乏国际治疗指南、许多治疗方式缺乏证据以及CDH患者相对较少,这就需要在治疗CDH患者方面具有专业知识的中心之间进行合作。国际CDH欧洲联盟就是这样一个合作网络的例子,它促进了知识交流、未来研究和治疗方案的开发。

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