Higgins P M
Epidemiol Infect. 1992 Oct;109(2):181-9. doi: 10.1017/s0950268800050147.
This report is based on a study of acute infections of the upper respiratory tract in 1965 and detailed records of such infections in 1963 and 1964. A change from illnesses mainly yielding viruses to illnesses mainly yielding group A streptococci was noted around the age of 5 years. A positive culture for group A streptococci in patients over 4 years of age was highly correlated with a complaint of sore throat and with serological evidence of streptococcal infection. A bimodal age distribution curve for pharyngitis associated with a positive culture for group A streptococci was consistently noted. The incidence was highest in children aged 5-9 but a second smaller peak occurred among adults in the 30-39 age group. The evidence suggests that being female increases the risk of acquiring group A streptococci and of experiencing sore throat.
本报告基于1965年对上呼吸道急性感染的研究以及1963年和1964年此类感染的详细记录。在5岁左右，注意到疾病类型从主要由病毒引起转变为主要由A组链球菌引起。4岁以上患者A组链球菌培养呈阳性与咽痛主诉以及链球菌感染的血清学证据高度相关。与A组链球菌培养阳性相关的咽炎呈现双峰年龄分布曲线，这一点始终存在。发病率在5 - 9岁儿童中最高，但在30 - 39岁的成年人中出现了第二个较小的峰值。有证据表明，女性感染A组链球菌和出现咽痛的风险增加。
