Schnurr B, Spatz W B, Illing R B
Unit for Morphological Brain Research, University Department of Otorhinoloryngology, Freiburg, Federal Republic of Germany.
Exp Brain Res. 1992;90(2):291-6. doi: 10.1007/BF00227240.
We studied the distribution of acetylcholinesterase activity and choline acetyltransferase immunoreactivity in the superior colliculus of the guinea pig and the albino rat, using enzyme histochemical and immunohistochemical methods. Choline acetyltransferase-like immunoreactivity was localized in the neuropil throughout the colliculi, but the density of the immunoreactive neuropil varied among layers as well as between species. In the intermediate collicular layers the pattern of choline acetyltransferase immunoreactivity was closely matched by the distribution of acetylcholinesterase activity in guinea pig and rat, confirming our previous findings in the cat. Furthermore, in the guinea pig, but not in the rat, choline acetyltransferase-like immunoreactivity was localized in a prominent population of perikarya of the superficial gray layer.
我们采用酶组织化学和免疫组织化学方法，研究了豚鼠和白化大鼠上丘中乙酰胆碱酯酶活性及胆碱乙酰转移酶免疫反应性的分布情况。胆碱乙酰转移酶样免疫反应性定位于整个上丘的神经毡中，但免疫反应性神经毡的密度在各层之间以及不同物种之间存在差异。在豚鼠和大鼠的上丘中间层，胆碱乙酰转移酶免疫反应性模式与乙酰胆碱酯酶活性分布紧密匹配，这证实了我们之前在猫身上的研究结果。此外，在豚鼠而非大鼠中，胆碱乙酰转移酶样免疫反应性定位于浅层灰质中一群突出的神经元胞体。
