RITTENBERG M B, NELSON E L
Science. 1962 Oct 26;138(3539):519-20. doi: 10.1126/science.138.3539.519.
Rabbits were injected with antigen 24 hours after x-irradiation. Antibody titers were correlated with relative changes in gamma-beta globulin levels determined electrophoretically. Irradiated, immunized rabbits did not form detectable antibodies but had significantly greater globulin levels than non-immunized, irradiated controls. This relative difference occurred at the time nonirradiated, immunized rabbits were producing primary antibody.
兔子在接受X射线照射24小时后注射抗原。抗体滴度与通过电泳测定的γ-β球蛋白水平的相对变化相关。接受照射并免疫的兔子未形成可检测到的抗体,但球蛋白水平明显高于未免疫的照射对照组。这种相对差异出现在未受照射但免疫的兔子产生初级抗体的时候。