Stirling J W, Chandler J A
Virchows Arch A Pathol Anat Histol. 1977 Mar 11;373(2):119-32. doi: 10.1007/BF00432157.
The ultrastructure of the ducts and subareolar ducts of the resting female breast have been described. In transverse section ducts have longitudinal folds, some of which are solid ridges of cells. Four distinctive cell types were distinguished; epithelial cells, lymphocyte type cells, basal clear cells and myoepithelial cells. The epithelium is single layered, multiple at folds, and similar in general morphology to the terminal ductal-lobular unit. Well developed terminal bars may prevent cellular disruption during contraction, and apical cytoplasmic vesicles represent possible secretory material. Basal cytoplasmic bodies may represent transport of secretory products into or from the periductal stroma. Intranuclear vesicles may also be linked to secretory activity. The myoepithelium is well differentiated with numerous cytoplasmic filaments and 9+0 cilia, forming a discontinuous layer around the epithelium. The basal lamina is generally multilaminate. Capillaries are 1-5mum in diameter and exterior to the delimiting fibroblasts of the epithelial-stromal junction.
已对静止期女性乳腺导管及乳晕下导管的超微结构进行了描述。在横切面上，导管有纵向褶皱，其中一些是细胞的实性嵴。区分出四种不同的细胞类型：上皮细胞、淋巴细胞样细胞、基底透明细胞和肌上皮细胞。上皮为单层，在褶皱处为多层，其一般形态与终末导管小叶单位相似。发育良好的终末棒可防止收缩时细胞破裂，顶端胞质小泡代表可能的分泌物质。基底胞质体可能代表分泌产物进出导管周围基质的转运。核内小泡也可能与分泌活动有关。肌上皮分化良好，有许多胞质细丝和9+0纤毛，在上皮周围形成不连续层。基膜通常为多层。毛细血管直径为1-5μm，位于上皮-基质交界处界定成纤维细胞的外侧。
