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大肠杆菌中戊糖的生物合成及生物合成途径。

Biosynthesis and biosynthetic pathways of pentoses in Escherichia coli.

作者信息

SABLE H Z, CASSISI E E

出版信息

J Bacteriol. 1962 Dec;84(6):1169-72. doi: 10.1128/jb.84.6.1169-1172.1962.

DOI:10.1128/jb.84.6.1169-1172.1962
PMID:13975889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC278041/
Abstract

Sable, Henry Z. (Western Reserve University, Cleveland, Ohio) and Elayne E. Cassisi. Biosynthesis and biosynthetic pathways of pentoses in Escherichia coli. J. Bacteriol. 84:1169-1172. 1962.-Resting glucose-adapted Escherichia coli supplied with glucose continues to synthesize pentose by the oxidative pathway characteristic of logarithmically growing glucose-adapted cells. This behavior is unlike that of acetate-adapted resting E. coli supplied with glucose, which continues to synthesize most of its pentose by the nonoxidative pathway characteristic of acetate-adapted cells. When infected with bacteriophage T2H, E. coli continues to use the oxidative pathway predominantly. This finding is in contrast to reports that infection with T6r+ bacteriophage increases the participation of a nonoxidative pathway. Resting glucose-adapted E. coli supplied with acetate-1-C(14) as sole carbon source synthesizes pentose by a pathway or pathways which cannot be assessed completely by methods previously developed (which are based on the relative labeling of C-1, C-2, and C-3 of the pentose) but which is most probably predominantly nonoxidative.

摘要

萨布尔,亨利·Z.(俄亥俄州克利夫兰市西储大学)和伊莱恩·E.卡西西。大肠杆菌中戊糖的生物合成及生物合成途径。《细菌学杂志》84:1169 - 1172。1962年。——用葡萄糖培养适应葡萄糖的静止型大肠杆菌,继续通过对数生长期适应葡萄糖的细胞所特有的氧化途径合成戊糖。这种行为与用葡萄糖培养适应乙酸盐的静止型大肠杆菌不同,后者继续通过适应乙酸盐的细胞所特有的非氧化途径合成其大部分戊糖。当被噬菌体T2H感染时,大肠杆菌继续主要使用氧化途径。这一发现与关于感染T6r⁺噬菌体增加非氧化途径参与度的报道形成对比。用乙酸盐 - 1 - C¹⁴作为唯一碳源培养适应葡萄糖的静止型大肠杆菌,通过一种或多种途径合成戊糖,这些途径无法用先前开发的方法(基于戊糖的C - 1、C - 2和C - 3的相对标记)完全评估,但很可能主要是非氧化途径。

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本文引用的文献

1
Growth of Escherichia coli and production of bacteriophage in defined media.大肠杆菌在限定培养基中的生长及噬菌体的产生。
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Biosynthesis of pentose in Escherichia coli. Synthesis of deoxyribose in cells infected with bacteriophage.大肠杆菌中戊糖的生物合成。感染噬菌体的细胞中脱氧核糖的合成。
J Bacteriol. 1961 Jun;81(6):845-51. doi: 10.1128/jb.81.6.845-851.1961.
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Biosynthesis of pentoses in Escherichia coli. Factors involved in selection of biosynthetic pathways.大肠杆菌中戊糖的生物合成。参与生物合成途径选择的因素。
J Bacteriol. 1961 Jun;81(6):837-44. doi: 10.1128/jb.81.6.837-844.1961.
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Nucleic acid metabolism and ribonucleic acid heterogeneity in Escherichia coli.大肠杆菌中的核酸代谢与核糖核酸异质性
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The origin of purine and pyrimidine deoxyribose in T6r+ bacteriophage.T6r+噬菌体中嘌呤和嘧啶脱氧核糖的起源
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On the origin of deoxyribose in Escherichia coli and T6r + bacteriophage.关于大肠杆菌和T6r+噬菌体中脱氧核糖的起源
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