Czekanowski R
Zentralbl Gynakol. 1977;99(2):98-105.
This paper presents the results of investigations on the dependence between the flow and intravascular pressure and uterine contractile activity. The pressure in the vascular bed was monitored with a pressure transducer and the contractile activity by means of an intrauterine ballon was measured. In a part of experiments, the flow was recorded with a flowmeter. The investigations were performed on 27 nonpregnant human uteri in various phases of the menstrual cycle. Uterus was perfused with a perfusion pump, starting from the perfusion pressure of 50 to 60 mm Hg and on up to maximum values of 140 mm Hg. It has been found that with an increase in the uterine flow, intravascular pressure increases too. This pressure-flow relationship is linear. An increase in flow through the nonpregnant uterus leads to an increase in intravascular pressure from 61.5 mm Hg to 142 mm Hg with a simultaneous increase in the human uterine basal tonus from the 6.2 mm Hg initial value to the average value of 25 mm Hg at the perfusion pressure of 140 mm Hg and an decrease in frequency from 6.6 to 5.2 contractions/10 min. With an increase of flow, however, there is a increase in amplitude which reaches highest values at the 100 mm Hg perfusion pressure and than no significant increase in amplitude is observed. An increase in amplitude is accompanied by an increase in contractile activity. It should be concluded that hemodynamic conditions and the state of vessels play a controlling role in the process of the uterine activity.
本文介绍了关于血流与血管内压力及子宫收缩活动之间相关性的研究结果。通过压力传感器监测血管床压力，并借助宫内球囊测量收缩活动。在部分实验中，用流量计记录血流。研究在27个处于月经周期不同阶段的非妊娠人体子宫上进行。子宫由灌注泵灌注，起始灌注压力为50至60毫米汞柱，最高可达140毫米汞柱的最大值。研究发现，随着子宫血流增加，血管内压力也会增加。这种压力 - 血流关系是线性的。流经非妊娠子宫的血流增加会导致血管内压力从61.5毫米汞柱增加到142毫米汞柱，同时人体子宫基础张力从初始值6.2毫米汞柱增加到灌注压力为140毫米汞柱时的平均值25毫米汞柱，频率从6.6次/10分钟降至5.2次/10分钟。然而，随着血流增加，振幅会增加，在灌注压力为100毫米汞柱时达到最高值，之后振幅无显著增加。振幅增加伴随着收缩活动增强。可以得出结论，血流动力学状况和血管状态在子宫活动过程中起控制作用。
