[Investigations of the human isolated nonpregnant uterus contractility in the course of the menstrual cycle by measuring intramyometrial pressure (author's transl)].

In this work, the behaviour of the intramyometrial pressure, registered in the wall of the myometrium of the human isolated nonpregnant uterus, has been followed up. Intramyometrial pressure measurements were performed in 33 uteri. Simultaneously the intravascular pressure was monitored. The values of the intramyometrial pressure correspond with the intrauterine pressure, and the pressure in the uterine cavity, measured with the use of inserted balloon, was a resultant of the intrauterine pressure measured in the corpus uteri and isthmus at the same time. It has been found that in the course of the sexual cycle, nonpregnant human uterus shows irregular contractile activity. The contractile activity of the nonpregnant human uterus is characterized by the lack of coordination of contractions among particular uterine regions registered simultaneously. During the course of the menstrual cycle the isthmus region was dominating and revealed a pacemaker properties and during menstrual bleeding corpus uteri dominated. The results were discussed and the close relationship between uterine contractility and intravascular pressure was underlined.