鱿鱼轴突膜对各种离子的通透性。
Permeability of squid axon membrane to various ions.
作者信息
TASAKI I
出版信息
J Gen Physiol. 1963 Mar;46(4):755-72. doi: 10.1085/jgp.46.4.755.
Abstract
The permeability of the squid axon membrane was determined by the use of radioisotopes of Na, K, Ca, Cs, and Br. Effluxes of these isotopes were measured mainly by the method of intracellular injection. Measurements of influxes were carried out under continuous intracellular perfusion with an isotonic solution of potassium sulfate. The Na permeability of the resting (excitable) axonal membrane was found to be roughly equal to the K permeability. The permeability to anion was far smaller than that to cations. It is emphasized that the axonal membrane has properties of a cation exchanger. The physicochemical nature of the "two stable states" of the excitable membrane is discussed on the basis of ion exchange isotherms.
摘要
利用钠、钾、钙、铯和溴的放射性同位素测定了鱿鱼轴突膜的通透性。这些同位素的外流主要通过细胞内注射法进行测量。内流的测量是在细胞内持续灌注硫酸钾等渗溶液的条件下进行的。发现静息（可兴奋）轴突膜的钠通透性大致等于钾通透性。对阴离子的通透性远小于对阳离子的通透性。强调轴突膜具有阳离子交换剂的特性。基于离子交换等温线讨论了可兴奋膜“两种稳定状态”的物理化学性质。
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