TURK J L
Immunology. 1962 Jul;5(4):478-88.
Delayed hypersensitivity to tuberculin and contact sensitivity to picryl chloride were transferred passively to normal guinea pigs by the intravenous injection of spleen, lymph node and peripheral blood mononuclear cells labelled with Cr or with P or H-thymidine. No significant difference was found between the number of injected cells arriving at the passive lesions and actively induced lesions in controls, after 24 hours. The proportion of labelled cells in the exudate was the same as that in the peripheral blood and they showed a random distribution throughout the lesion. The fate of labelled cells in the body was followed, especially their role of elimination from the lungs and peripheral blood. It was concluded that no special affinity of the transferred cells for antigen could be demonstrated after 24 hours.
通过静脉注射用铬或磷或 H-胸腺嘧啶标记的脾、淋巴结和外周血单核细胞，将对结核菌素的迟发型超敏反应和对氯化苦基的接触敏感性被动转移至正常豚鼠。24 小时后，到达被动损伤部位的注射细胞数量与对照组中主动诱导损伤部位的细胞数量之间未发现显著差异。渗出液中标记细胞的比例与外周血中的比例相同，且它们在整个损伤部位呈随机分布。追踪了体内标记细胞的去向，尤其是它们从肺和外周血中清除的作用。得出的结论是，24 小时后无法证明转移细胞对抗原有特殊亲和力。
