Holzmann H, Schlieter A, Altmeyer P, Kühnl P
Abteilung I, Johann-Wolfgang-Goethe-Universität Frankfurt/Main.
Hautarzt. 1992 Sep;43(9):548-53.
Two different forms of scleroderma in one family are described: the mother suffers from systemic sclerosis and her daughter from linear morphoea. The observed HLA antigens indicate that systemic sclerosis and morphoea have various features in common. The immunogenetic data can be used to calculate the aetiological and preventive fractions, which together with environmental hazards and other risk factors describe the HLA-associated potential for provocation of scleroderma.
母亲患有系统性硬化症，女儿患有线状硬斑病。观察到的 HLA 抗原表明，系统性硬化症和硬斑病有多种共同特征。免疫遗传学数据可用于计算病因学和预防分数，这些分数与环境危害和其他风险因素一起描述了 HLA 相关的硬皮病诱发潜力。
