Baldauf C, Schaller J, Herrmann K, Haustein U F
Dermatol Monatsschr. 1989;175(1):16-9.
In 41 patients suffering from progressive systemic sclerosis (PSS) the phenotype frequencies of 28 HLA-A, B, C antigens were determined. Compared to 2947 blood donors the PSS patients exhibited an increase in the HLA-B8 frequency (37% versus 19%). This difference revealed to be not significant after the correction according to the number of antigens tested. The same was with the increase in the frequency of HLA-B5, B13, B27, Cw2 and the decrease in the frequency of HLA-A2, B12, B14, B15, B4 and Cw3. The results were compared with the data reported in the literature. Additionally, there were no differences when compared the diffuse PSS with the acral form and CREST, respectively.
在41例进行性系统性硬化症（PSS）患者中，测定了28种HLA - A、B、C抗原的表型频率。与2947名献血者相比，PSS患者的HLA - B8频率有所增加（37%对19%）。根据所检测抗原数量进行校正后，这一差异无统计学意义。HLA - B5、B13、B27、Cw2频率的增加以及HLA - A2、B12、B14、B15、B4和Cw3频率的降低情况亦是如此。将结果与文献报道的数据进行了比较。此外，弥漫性PSS分别与肢端型PSS和CREST综合征相比时，无差异。
