五种外切核糖核酸酶中仅有一种的存在就足以支持大肠杆菌的生长。
The presence of only one of five exoribonucleases is sufficient to support the growth of Escherichia coli.
作者信息
Kelly K O, Deutscher M P
机构信息
Department of Biochemistry, University of Connecticut Health Center, Farmington 06030-3305.
出版信息
J Bacteriol. 1992 Oct;174(20):6682-4. doi: 10.1128/jb.174.20.6682-6684.1992.
Abstract
Escherichia coli contains multiple exoribonucleases. Strains lacking the exoribonucleases RNase II, D, BN, T, and PH are inviable. The introduction of a chromosomal, wild-type copy of the gene for any one of these enzymes is sufficient to allow cell growth, with the enzymes being in the following order of effectiveness: RNase T > RNase PH > RNase D > RNase II > RNase BN. The data indicate that these five exoribonucleases functionally overlap in vivo and that any one of them can take over the functions of all the others, although with various efficiencies.
摘要
大肠杆菌含有多种外切核糖核酸酶。缺乏外切核糖核酸酶RNase II、D、BN、T和PH的菌株无法存活。引入这些酶中任何一种的基因的染色体野生型拷贝足以使细胞生长，这些酶的有效性顺序如下：RNase T > RNase PH > RNase D > RNase II > RNase BN。数据表明，这五种外切核糖核酸酶在体内功能上相互重叠，其中任何一种都可以接管其他所有酶的功能，尽管效率各不相同。
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