Pugsley A P, Reeves P
J Bacteriol. 1977 Apr;130(1):26-36. doi: 10.1128/jb.130.1.26-36.1977.
The uptake of the siderophore-iron complex ferrienterochelin was found to be strongly dependent upon an energized membrane state, as demonstrated by its sensitivity to dinitrophenol, azide, and cyanide. Ferrienterochelin uptake may also be dependent upon phosphate bond energy, as indicated by sensitivity to arsenate and iodoacetic acid. Although the adenosine triphosphatase does not appear to be involved in this energy coupling mechanism, ferrienterochelin uptake was shown to be less dependent upon phosphate bond energy than was glutamine uptake. Sensitivity of ferrienterochelin uptake to osmotic shock was shown to be due to the release of a ferrienterochelin binding compound located in the outer membrane of the cells and probably identical to the colicin B receptor protein.
已发现铁载体 - 铁复合物肠螯合铁的摄取强烈依赖于有能量的膜状态，这可通过其对二硝基苯酚、叠氮化物和氰化物的敏感性来证明。肠螯合铁的摄取也可能依赖于磷酸键能，这可通过其对砷酸盐和碘乙酸的敏感性来表明。尽管三磷酸腺苷酶似乎不参与这种能量偶联机制，但已表明肠螯合铁的摄取比谷氨酰胺的摄取对磷酸键能的依赖性更小。肠螯合铁摄取对渗透压休克的敏感性被证明是由于位于细胞外膜的一种肠螯合铁结合化合物的释放，该化合物可能与大肠杆菌素B受体蛋白相同。
