Madhusudana S N, Aggarwal P
Rabies Research Centre, Central Research Institute, Kasauli.
J Indian Med Assoc. 1992 Jul;90(7):169-71.
Epidemiological and laboratory studies were conducted on 80 clinically diagnosed human rabies cases. Incidence of rabies was more in adult males (55%) and boys (37.5%) than adult females (5%) and girls (2.5%) and more in rural areas (76.2%) than urban areas (23.8%). Dogs constituted the main vector of transmission (92.5%). Incomplete course of antirabic vaccine had been received by 31% of cases and 2.5% of cases had complete course of antirabic vaccine. Among the laboratory tests conducted 3.8% of corneal smears and 2.5% of saliva smears were positive by fluorescent antibody technique. Rabies virus was isolated from 3.8% of saliva and 3% of cerebrospinal fluid samples. Rabies neutralising antibody titre ranged from 1:64 to 1:128 in the serum of patients who were fully vaccinated.
对80例临床诊断的人类狂犬病病例进行了流行病学和实验室研究。狂犬病发病率在成年男性（55%）和男孩（37.5%）中高于成年女性（5%）和女孩（2.5%），在农村地区（76.2%）高于城市地区（23.8%）。狗是主要的传播媒介（92.5%）。31%的病例接受了不完整疗程的抗狂犬病疫苗，2.5%的病例接受了完整疗程的抗狂犬病疫苗。在进行的实验室检测中，3.8%的角膜涂片和2.5%的唾液涂片通过荧光抗体技术呈阳性。从3.8%的唾液和3%的脑脊液样本中分离出狂犬病病毒。在完全接种疫苗的患者血清中，狂犬病中和抗体滴度范围为1:64至1:128。
