Fukuchi T, Ohkawa Y, Koike S, Kubo K, Murase K
Department of Cardiovascular Surgery, National Sanatorium Toyohashi Higashi Hospital, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1992 Sep;40(9):1767-72.
Right ventricular assistance (RVA) using centrifugal pump in combination with IABP was used to treat a patient who was difficult to wean from a cardiopulmonary bypass following emergency coronary revascularization and resection of a ventricular aneurysm performed to treat acute right ventricular infarction due to a PTCA complication. After 131 hours of RVA at 3.2 to 4.8 l/min, it was possible to remove the pump. No heparin was administered during this time, changing the pump head twice, was used for 64 and 50 hour period, no thrombi were detected either time. After being weaned from RVA, the patient developed severe respiratory dysfunction, but on the 10th postoperative day (POD) IABP was weaned, and on the 13th POD the artificial respirator was withdrawn. The results of the postoperative cardiac catheterization were favorable, the patient was discharged on the 57th POD, and has returned to society at the present time. The indications for RVA include a central venous pressure > 20 mmHg and a cardiac index < 1.8 l/min/m2, and tissue perfusion pressure and general preoperative condition should severe as guides. The higher the assisted flow volume the more efficacious in relieving ventricular load, but, since there is a limit to how much the left ventricle and lungs can withstand, it should not exceed levels which ensure the maintainance of cardiac output and tissue perfusion pressure.
采用离心泵联合主动脉内球囊反搏(IABP)进行右心室辅助(RVA),治疗一名因经皮冠状动脉腔内血管成形术(PTCA)并发症导致急性右心室梗死,在急诊冠状动脉血运重建和心室瘤切除术后难以脱离体外循环的患者。在以3.2至4.8升/分钟的流量进行131小时的RVA后,成功撤泵。在此期间未使用肝素,两次更换泵头,分别使用64小时和50小时,两次均未检测到血栓。脱离RVA后,患者出现严重呼吸功能障碍,但在术后第10天撤掉IABP,术后第13天撤掉人工呼吸机。术后心脏导管检查结果良好,患者于术后第57天出院,目前已重返社会。RVA的适应证包括中心静脉压>20 mmHg且心脏指数<1.8升/分钟/平方米,应以组织灌注压和术前一般状况作为指导。辅助流量越高,减轻心室负荷的效果越显著,但由于左心室和肺的耐受能力有限,辅助流量不应超过确保维持心输出量和组织灌注压的水平。