McDonald M N, Vire D E
U.S. Army Dental Corps, Fort Sill, OK.
J Endod. 1992 Jun;18(6):301-3. doi: 10.1016/s0099-2399(06)80958-1.
This article reviews the role chloroform has played in dentistry and describes an occupational health clinical investigation into the possible hazards of chloroform use in the operatory. Due to a Food and Drug Administration ban on drugs and cosmetics containing chloroform, there has been some confusion as to whether the use of chloroform in the practice of dentistry is considered unsafe or has been prohibited. Utilizing common endodontic treatment methods employing chloroform, this study reports no negative health effects to the dentist or assistant and air vapor levels well below Occupational Health and Safety Administration mandated maximum levels. The report concludes that, with careful and controlled use, chloroform can be a useful adjunct in the practice of dentistry. The Food and Drug Administration has no jurisdiction over a dentist's use of chloroform in clinical practice and has not proven that chloroform is a human carcinogen.
本文回顾了氯仿在牙科领域所起的作用，并描述了一项职业健康临床调查，该调查针对在牙科诊疗室使用氯仿可能存在的危害展开。由于美国食品药品监督管理局禁止含有氯仿的药品和化妆品，对于在牙科实践中使用氯仿是否被视为不安全或已被禁止存在一些混淆。本研究采用了使用氯仿的常见牙髓治疗方法，报告称对牙医或助手没有负面健康影响，且空气蒸汽水平远低于职业健康与安全管理局规定的最高水平。报告得出结论，在谨慎且可控的使用下，氯仿可以成为牙科实践中的一种有用辅助手段。美国食品药品监督管理局对牙医在临床实践中使用氯仿没有管辖权，也未证明氯仿是一种人类致癌物。
