[Study of arteriosclerosis in different geographical zones of the Soviet Union. II. The fatty acid makeup of the lipids of the vascular wall in inhabitants of Uzbekistan].

A detailed description is presented for the fatty acids composition of the ether fractions of cholesterol, triglycerides and phospholipids in the normal aortic intima and at various stages of atherosclerosis in indigenous population (Uzbeks) and migrant (Russian) population of Uzbekistan. The most significant changes were revealed in the cholesterol ethers. At various stages of atherosclerosis the changes in the fatty acids of cholesterol ethers are not identical and depend on the nature of the lesion. The relative content of the oleic acid is usually higher, and that of the linoleic--lower in the fat strands and spots, than in the unchanged aortic intima. In the atheromatous plaques, on the contrary, the content of the linoleic acid increases, and that of the oleic--decreases. With age, the content of the linoleic acid increases even in the portions of the intima free of atherosclerosis. The relative content of linoleic acid in the triglycerides of the normai intima and in the atheromatous plaques is higher in the indigenous population of Uzbekistan, than in the migrants.