Wignall F S, Hyams K C, Phillips I A, Escamilla J, Tejada A, Li O, Lopez F, Chauca G, Sanchez S, Roberts C R
U.S. Naval Medical Research Institute Detachment, Lima, Peru.
J Med Virol. 1992 Sep;38(1):44-8. doi: 10.1002/jmv.1890380110.
The epidemiology of HTLV-I infection in female prostitutes was studied in a survey of 395 prostitutes from Callao, Peru (the port city of Lima), 72 prostitutes from Iquitos, Peru (another port city on the Amazon River), and 510 prenatal clinic patients from Lima. Prostitutes reported a mean of 8.8 years (range, 1-39 years) of active prostitution and a mean of 205 sexual contacts during the month prior to the study. The percentage of prostitutes with HTLV-I antibody (21.8%) was significantly higher than patients attending a prenatal clinic (3.1%; P less than .0001). The prevalence of HTLV-I antibody increased steadily with age in prostitutes, but no age trend was noted in prenatal patients. By multiple logistic regression analysis, an independent association was found between HTLV-I seropositivity and a history of prostitution in Callao, age, and positive syphilis serology when all 977 study subjects were evaluated. When prostitutes alone were analyzed, the number of years of exposure as a practicing prostitute was associated with HTLV-I seropositivity after controlling for age. These data indicate a greatly increased risk of HTLV-I infection in prostitutes in Callao, Peru, and suggest an association between sexual activity and HTLV-I transmission.
在一项针对来自秘鲁卡亚俄（利马的港口城市）的395名妓女、来自秘鲁伊基托斯（亚马逊河上的另一个港口城市）的72名妓女以及来自利马的510名产前诊所患者的调查中，对人类嗜T淋巴细胞病毒I型（HTLV-I）感染的流行病学情况进行了研究。妓女们报告称，在研究前一个月，她们平均从事性交易活动8.8年（范围为1至39年），平均有205次性接触。携带HTLV-I抗体的妓女比例（21.8%）显著高于产前诊所的患者（3.1%；P<0.0001）。在妓女中，HTLV-I抗体的患病率随年龄稳步上升，但在产前患者中未发现年龄趋势。通过多因素逻辑回归分析，在对所有977名研究对象进行评估时，发现HTLV-I血清阳性与在卡亚俄的卖淫史、年龄以及梅毒血清学阳性之间存在独立关联。当仅对妓女进行分析时，在控制年龄因素后，从事性交易活动的年限与HTLV-I血清阳性相关。这些数据表明，秘鲁卡亚俄的妓女感染HTLV-I的风险大幅增加，并提示性活动与HTLV-I传播之间存在关联。
