Martin L, Edworthy S M, Ryan J P, Fritzler M J
Department of Medicine, University of Calgary, AB, Canada.
J Rheumatol. 1992 Aug;19(8):1186-90.
We report the occurrence of life threatening upper airway complications in 4 of 158 patients with systemic lupus erythematosus (SLE) admitted to our hospital over a 6-year period and review published reports on this complication. The patients included in our study were identified through a computer search of our hospital medical records. Patients' charts were reviewed and the diagnosis confirmed by currently accepted criteria. The clinical features of SLE in all the published cases were assessed and compared to those found in our patients. We found that although upper airway involvement is uncommon in SLE, occurring with a relative frequency of 4/158 patient admissions, endotracheal intubation in patients with active SLE may result in the development of life threatening upper airway complications. We suggest that patients with active SLE who require intubation should be observed for the development of upper airway symptoms.
我们报告了在6年期间我院收治的158例系统性红斑狼疮（SLE）患者中有4例出现危及生命的上呼吸道并发症，并回顾了关于该并发症的已发表报告。我们研究中的患者是通过对我院病历进行计算机检索确定的。查阅了患者的病历，并根据目前公认的标准确诊。评估了所有已发表病例中SLE的临床特征，并与我们患者的特征进行了比较。我们发现，虽然上呼吸道受累在SLE中并不常见，在158例患者入院中相对发生率为4例，但活动性SLE患者进行气管插管可能会导致危及生命的上呼吸道并发症。我们建议，需要插管的活动性SLE患者应密切观察是否出现上呼吸道症状。
