SORGER K
Can Med Assoc J. 1963 Sep 7;89(10):503-7.
One variety of sarcoma of the central nervous system (CNS) has been referred to under such synonyms as perithelial sarcoma, microglioma, and reticulum cell sarcoma. A case of diffuse involvement of the CNS is reported and the author believes that the tumour is a reticulum cell sarcoma because: (1) in addition to involvement of the CNS, lesions characteristic of a diffuse lymphomatous process were present in extraneural sites; (2) silver carbonate impregnation of the tumour cells was demonstrated. This tinctorial property has been reported as characteristic of microgliomas but has been shown to be an unreliable criterion for the differentiation of the cells of microglial from those of reticulum cell sarcomas. It is concluded that in such cases the CNS is the initial and major focus of a multicentric malignant lymphoma which has the histologic characteristics of a reticulum cell sarcoma.
中枢神经系统(CNS)的一种肉瘤曾被称为血管外皮肉瘤、小胶质细胞瘤和网状细胞肉瘤等同义词。本文报告了1例CNS弥漫受累的病例,作者认为该肿瘤是网状细胞肉瘤,原因如下:(1)除CNS受累外,神经外部位还存在弥漫性淋巴瘤样病变的特征;(2)肿瘤细胞经碳酸银浸染得到证实。这种染色特性曾被报道为小胶质细胞瘤的特征,但已证明它并不是区分小胶质细胞和网状细胞肉瘤细胞的可靠标准。结论是,在这类病例中,CNS是多中心恶性淋巴瘤的初始和主要病灶,该淋巴瘤具有网状细胞肉瘤的组织学特征。