丁酰磷酸在破伤风梭状芽孢杆菌能量代谢中的作用
ROLE OF BUTYRYL PHOSPHATE IN THE ENERGY METABOLISM OF CLOSTRIDIUM TETANOMORPHUM.
作者信息
TWAROG R, WOLFE R S
出版信息
J Bacteriol. 1963 Jul;86(1):112-7. doi: 10.1128/jb.86.1.112-117.1963.
Abstract
Twarog, R. (University of Illinois, Urbana) and R. S. Wolfe. Role of butyryl phosphate in the energy metabolism of Clostridium tetanomorphum. J. Bacteriol. 86:112-117. 1963.-A partially purified butyrokinase from Clostridium tetanomorphum has been found to phosphorylate valerate, butyrate, isobutyrate, and propionate. The divalent cation requirement is satisfied with magnesium. The pH optimum lies between 7.4 and 8.3. Growth of the organism was followed using glutamate or histidine as substrate, butyrokinase being formed in each instance. The average dry weight of cells formed per mmole of substrate utilized was 6.8 mg for glutamate and 11.1 mg for histidine. Since both phosphotransbutyrylase and butyrokinase are present in the cells, it is proposed that a significant portion of energy derived from glutamate oxidation by this organism is obtained from butyryl phosphate.
摘要
特瓦罗格，R.（伊利诺伊大学厄巴纳分校）和R.S.沃尔夫。丁酰磷酸在破伤风梭状芽孢杆菌能量代谢中的作用。《细菌学杂志》86:112 - 117。1963年。——已发现来自破伤风梭状芽孢杆菌的部分纯化的丁酸激酶可使戊酸、丁酸、异丁酸和丙酸磷酸化。二价阳离子需求可用镁来满足。最适pH值在7.4至8.3之间。以谷氨酸或组氨酸为底物跟踪该生物体的生长情况，在每种情况下均会形成丁酸激酶。每利用1毫摩尔底物形成的细胞平均干重，以谷氨酸为底物时为6.8毫克，以组氨酸为底物时为11.1毫克。由于细胞中同时存在磷酸转丁酰酶和丁酸激酶，因此有人提出该生物体通过谷氨酸氧化获得的能量的很大一部分来自丁酰磷酸。
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