Biederman A, Walczak F, Rembelska H, Jedynak Z, Kepski R, Bujnowska E, Sliwiński M, Rydlewska-Sadowska W, Hoffman M
I Kliniki Kardiochirurgii, Instytut Kardiologii w Warszawie.
Kardiol Pol. 1992 Jul;37(7):13-7.
Successful dissection of accessory pathways (AcP's) was performed in 19 of 20 patients. 15 pts had single, 4 double and 1 patient had 3 accessory pathways (AcP's). The patient with 3 AcP's was operated twice. During the first operation two AcP's were eliminated. The third one was revealed during the postoperative electrophysiologic study. Verapamil facilitated its manifestation and localisation. No patient had syncope or atrio-ventricular tachycardia after the operation. In 3 of 10 patients who had atrial fibrillation before the operation, episodes of AF occurred in the early postoperative period. Conduction to the ventricles was through the normal conduction system. Dissection of AcP's prevented extremely fast ventricular response and syncope. After discontinuation of amiodarone more frequent ventricular premature beats occurred in patients with long history of cardiac arrhythmias, on drugs for a long time and in patients who had heart dilatation. Several months after the operation VEB were less frequent, probably because tachycardias did not occur, left ventricle geometry improved, and cardiodepressant drugs were discontinued. Previously these patients had been treated usually with combination of 2-3 such drugs. After the successful dissection of AcP's the patients lost the feeling of illness and do not feel being imperilled. Children can attend schools normally and some adult patients resumed their professional activities.
20例患者中有19例成功完成了旁路(AcP)的分离。15例患者有单条旁路,4例有两条旁路,1例患者有3条旁路(AcP)。有3条AcP的患者接受了两次手术。第一次手术时消除了两条AcP。第三条在术后电生理研究中被发现。维拉帕米有助于其显现和定位。术后无患者出现晕厥或房室性心动过速。术前有房颤的10例患者中,3例在术后早期出现房颤发作。心室传导通过正常传导系统。AcP的分离预防了极快速的心室反应和晕厥。在长期患有心律失常、长期服用药物以及有心脏扩大的患者中,停用胺碘酮后室性早搏更频繁。术后数月室性早搏频率降低,可能是因为未发生心动过速、左心室形态改善以及停用了心脏抑制药物。此前这些患者通常接受2 - 3种此类药物的联合治疗。成功分离AcP后,患者不再有患病的感觉,也不觉得有危险。儿童能够正常上学,一些成年患者恢复了职业活动。