Konrad D, Amato M
Abt. für Neonatologie, Kinderklinik Aarau und Universitäts-Frauenklinik Bern.
Klin Padiatr. 1992 Sep-Oct;204(5):362-7. doi: 10.1055/s-2007-1025373.
The cranial ultrasound of 111 preterm infants were reviewed. 57 patients were appropriate for gestational age (AGA) and 54 small for gestational age (SGA). In the two groups, the incidence of peri-intraventricular hemorrhage (PIVH), posthemorrhagic ventricular dilation (VM) and peri-ventricular leucomalacia (PVL) was compared. PIVH was more common in AGA than in SGA babies (36.8% vs 18.5%). In both groups (AGA and SGA), birth weight less than 1000 g should be considered a further risk factor for hemorrhagic brain lesion (72.2% in AGA babies less than 1000 g and 20.5% ind AGA babies greater than 1000 g birth weight, p less than 0.01) (34.8% in SGA babies less than 1000 g and 6.4% in SGA babies greater than 1000 g birth weight, p less than 0.05). However, ischemic brain lesions (PVL) were not dependent from birth weight (p greater than 0.5). This study shows that low birth weight infants are an eterogeneous group of babies with different risk of hemorrhagic or ischemic cerebral lesion depending on gestational age and birth weight.
对111例早产儿的头颅超声检查结果进行了回顾。57例患儿为适于胎龄儿（AGA），54例为小于胎龄儿（SGA）。比较了两组患儿脑室周围-脑室内出血（PIVH）、出血后脑室扩张（VM）和脑室周围白质软化（PVL）的发生率。PIVH在AGA患儿中比SGA患儿更常见（36.8%对18.5%）。在两组（AGA和SGA）中，出生体重小于1000g应被视为出血性脑损伤的另一个危险因素（出生体重小于1000g的AGA患儿中为72.2%，出生体重大于1000g的AGA患儿中为20.5%，p<0.01）（出生体重小于1000g的SGA患儿中为34.8%，出生体重大于1000g的SGA患儿中为6.4%，p<0.05）。然而，缺血性脑损伤（PVL）与出生体重无关（p>0.5）。本研究表明，低出生体重儿是一组异质性婴儿，根据胎龄和出生体重，其发生出血性或缺血性脑损伤的风险不同。
