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自然流产中夫妻混合白细胞培养的细胞免疫和体液免疫方面

Cellular and humoral immune aspects in mixed wife-husband leukocyte cultures in spontaneous abortions.

作者信息

Halbrecht I, Komlos L

出版信息

Acta Eur Fertil. 1976 Sep;7(3):249-55.

PMID:140575
Abstract

The possible role of feto--maternal cell--and humoral mediated immunological reactions, in mixed wife-husband one- and two-way stimulated leukocyte cultures (MWHLC) in autologous serum were investigated in a comparative study of 27 cases of normal and abnormal pregnancies (8 control and 19 cases of spontaneous abortions). Sera obtained from women after spontaneous abortions had a significantly higher stimulating effect on MWHLC than sera from women with normal pregnancies. In one-way stimulated MWHLC in cases of abortions, this effect was evident on maternal responding cells incubated with mitomycin treated paternal leukocytes.

摘要

在一项对27例正常和异常妊娠(8例对照和19例自然流产)的比较研究中,调查了胎儿-母体细胞和体液介导的免疫反应在自体血清中混合夫妻单向和双向刺激白细胞培养(MWHLC)中的可能作用。自然流产后妇女的血清对MWHLC的刺激作用明显高于正常妊娠妇女的血清。在流产病例的单向刺激MWHLC中,这种作用在与丝裂霉素处理的父方白细胞一起孵育的母体反应细胞上很明显。

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1
Cellular and humoral immune aspects in mixed wife-husband leukocyte cultures in spontaneous abortions.自然流产中夫妻混合白细胞培养的细胞免疫和体液免疫方面
Acta Eur Fertil. 1976 Sep;7(3):249-55.
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