基于形态学的病毒颗粒分类

Can Med Assoc J. 1963 Oct 19;89(16):787-98.

Recent improvements in electron microscope techniques which allow the study of virus fine structure have permitted the grouping of many viruses on a purely morphological basis. Briefly the techniques used in electron microscopy for the study of viruses are reviewed and the symmetry properties of virus particles as revealed by negative staining are discussed somewhat more fully.Finally, virus particles are grouped on two bases, firstly the site of formation of the virus within the cell as seen by thin sectioning techniques, and secondly the symmetry property of the virus as seen by negative staining. Consideration of the groupings obtained in this way reveals that the biochemical and physical properties of a virus can be deduced from the readily established morphological characteristics.

电子显微镜技术的最新进展使得对病毒精细结构的研究成为可能，这使得许多病毒能够在纯粹的形态学基础上进行分类。简要回顾了用于病毒研究的电子显微镜技术，并更全面地讨论了通过负染色揭示的病毒颗粒的对称性质。最后，病毒颗粒基于两个依据进行分类，首先是通过超薄切片技术观察到的病毒在细胞内的形成位点，其次是通过负染色观察到的病毒的对称性质。对以这种方式获得的分类的思考表明，病毒的生化和物理性质可以从容易确定的形态特征中推导出来。