Yajima H, Tamai S, Mizumoto S, Sugimura M, Horiuchi K
Department of Orthopaedic Surgery, Nara Medical University, Kashihara, Japan.
Microsurgery. 1992;13(5):227-33. doi: 10.1002/micr.1920130504.
From 1982 to 1991, 19 patients at Nara Medical University, Kashihara, Japan, underwent resection of aggressive benign and malignant bone tumors, with limb salvage and reconstruction by free vascularized fibula grafts. The patients were followed up for an average of 54 months. The reconstructed site was the jaw in 6 cases, upper extremity in 3, spine in 1, pelvis in 2, and lower extremity in 7. Six patients had aggressive benign lesions, and 13 had malignant lesions. The sizes of the resultant bone defect ranged from 6 to 20 cm, and the lengths of fibular used ranged from 8 to 24 cm. The average time to union was 4.1 months (2-9 months) in the extremities and pelvis. Local recurrence was observed in 3 cases, for whom vascularized fibula grafts were performed for recurrent tumors. In cases of primary untreated tumors, no recurrences occurred. Therefore, this procedure should be performed at the time of primary operation after extensive resection of an aggressive benign or malignant bone tumor.
1982年至1991年，日本奈良县柏原市奈良医科大学的19例患者接受了侵袭性良性和恶性骨肿瘤切除术，并采用游离带血管腓骨移植进行保肢和重建。对患者进行了平均54个月的随访。重建部位为颌骨6例，上肢3例，脊柱1例，骨盆2例，下肢7例。6例为侵袭性良性病变，13例为恶性病变。所形成的骨缺损大小为6至20厘米，所用腓骨长度为8至24厘米。四肢和骨盆的平均愈合时间为4.1个月（2至9个月）。3例出现局部复发，对复发性肿瘤进行了带血管腓骨移植。在原发性未治疗肿瘤的病例中，未发生复发。因此，该手术应在广泛切除侵袭性良性或恶性骨肿瘤后的初次手术时进行。
