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新型抗真菌抗生素分枝菌素的作用方式

MODE OF ACTION OF MYCOBACILLIN, A NEW ANTIFUNGAL ANTIBIOTIC.

作者信息

BANERJEE N, BOSE S K

出版信息

J Bacteriol. 1963 Sep;86(3):387-91. doi: 10.1128/jb.86.3.387-391.1963.

Abstract

Banerjee, N. (Calcutta University, Calcutta, India) and S. K. Bose. Mode of action of mycobacillin, a new antifungal antibiotic. J. Bacteriol. 86:387-391. 1963.-Mycobacillin agglutinates cells of Candida albicans. The agglutination reaction was found to be dependent on temperature, pH level, etc. Experiments have also been planned to assess whether agglutination and antifungal action are causally related. It appears that agglutination may be a secondary late effect of the action of the drug, not causally related to but simply associated with the primary cause responsible for antifungal action.

摘要

班纳吉,N.(印度加尔各答大学,加尔各答)和S.K.博斯。新型抗真菌抗生素分枝杆菌素的作用方式。《细菌学杂志》86:387 - 391。1963年。——分枝杆菌素可凝集白色念珠菌细胞。发现凝集反应取决于温度、pH值等。还计划进行实验以评估凝集作用与抗真菌作用是否存在因果关系。看来凝集作用可能是药物作用的一种继发性晚期效应,与抗真菌作用的主要原因没有因果关系,而只是与之相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2692/278447/558b9b73b866/jbacter00449-0053-a.jpg

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