van der Lugt A, Kranendonk S E, Baars A M
Afd. Chirurgie, Maria Ziekenhuis, Tilburg.
Ned Tijdschr Geneeskd. 1992 Sep 26;136(39):1910-3.
To detect familial occurrence of abdominal aortic aneurysms (AAA), the siblings of patients with an AAA were screened by ultrasonography. 128 siblings of 32 patients operated on for AAA were invited. 56 brothers and 52 sisters accepted the invitation. An AAA was diagnosed in 16 brothers (28.6%) and in 3 sisters (5.8%). Six of these siblings were operated on because of an aneurysmal diameter 20 mm in excess of that of the rest of the abdominal aorta, the others were included in a follow-up programme. We conclude that the prevalence of the AAA among brothers is higher in comparison with previously known risk groups and that the family of patients with an AAA are to be considered for screening first.
为检测腹主动脉瘤(AAA)的家族性发病情况,对AAA患者的兄弟姐妹进行了超声检查筛查。邀请了32例接受AAA手术患者的128名兄弟姐妹。56名兄弟和52名姐妹接受了邀请。在16名兄弟(28.6%)和3名姐妹(5.8%)中诊断出AAA。这些兄弟姐妹中有6人因动脉瘤直径比腹主动脉其他部位超出20毫米而接受了手术,其他人则被纳入随访计划。我们得出结论,与先前已知的风险群体相比,兄弟中AAA的患病率更高,并且应首先考虑对AAA患者的家族成员进行筛查。