Kimura S, Unayama T, Mori T
Department of Pediatrics, Yokohama City University School of Medicine, Japan.
Neuropediatrics. 1992 Aug;23(4):192-5. doi: 10.1055/s-2008-1071339.
The natural history of acute disseminated (leuko)encephalitis (ADE) in a 3-year-old girl who did not receive steroid therapy is reported. Serial MR studies disclosed: 1) white matter lesions resolved spontaneously, though very slowly, 2) active disease persisted for around three months and coincided with the onset of new subcortical lesions. These subcortical lesions were associated with hyperactivity, suggesting a possible etiologic correlation.
报告了一名未接受类固醇治疗的3岁女孩急性播散性（白质）脑炎（ADE）的自然病程。系列磁共振成像研究显示：1）白质病变虽自发消退但非常缓慢，2）活动性疾病持续约三个月，与新的皮质下病变出现同时发生。这些皮质下病变与多动有关，提示可能存在病因学关联。
