Hannut R, Duchateau J, Mascart F, Staquet E, Vainsel H, Bernard R
Service de Cardiologie, Hôpital Universitaire Saint-Pierre, Bruxelles, Belgique.
Pathol Biol (Paris). 1992 Jun;40(6):632-7.
Serum immunoglobulin (Ig) levels were assayed in 672 patients admitted for acute myocardial infarction with onset within 24 hours of hospitalization. Supranormal Ig levels (A > or = 300, G > or = 1,200) or subnormal Ig levels (M < 40 mg/100 ml) were seen in patients with one or several risk factors (diabetes mellitus, alcohol abuse) or a history of previous myocardial infarction. Patients with one or more Ig anomalies were more likely to exhibit unfavorable outcomes, including early death, suggesting that increased viscosity due to aggregation of Ig molecules may occur.
对672例入院后24小时内发病的急性心肌梗死患者检测了血清免疫球蛋白(Ig)水平。在有一个或多个危险因素(糖尿病、酗酒)或既往有心肌梗死病史的患者中,发现Ig水平超常(A≥300,G≥1200)或Ig水平低于正常(M<40mg/100ml)。有一项或多项Ig异常的患者更有可能出现不良后果,包括早期死亡,这表明可能发生了由于Ig分子聚集导致的血液黏稠度增加。