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大鼠脑内室管膜的精细结构

THE FINE STRUCTURE OF EPENDYMA IN THE BRAIN OF THE RAT.

作者信息

BRIGHTMAN M W, PALAY S L

出版信息

J Cell Biol. 1963 Nov;19(2):415-39. doi: 10.1083/jcb.19.2.415.

DOI:10.1083/jcb.19.2.415
PMID:14086765
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2106872/
Abstract

The ciliated ependyma of the rat brain consists of a sheet of epithelial cells, the luminal surface of which is reflected over ciliary shafts and numerous evaginations of irregular dimensions. The relatively straight lateral portions of the plasmalemma of contiguous cells are fused at discrete sites to form five-layered junctions or zonulae occludentes which obliterate the intercellular space. These fusions occur usually at some distance below the free surface either independently or in continuity with a second intercellular junction, the zonula adhaerens. The luminal junction is usually formed by a zonula adhaerens or, occasionally, by a zonula occludens. The finely granular and filamentous cytoplasm contains supranuclear dense bodies, some of which are probably lysosomes and dense whorls of perinuclear filaments which send fascicles toward the lateral plasmalemma. The apical regions of the cytoplasm contain the basal body complexes of neighboring cilia. These complexes include a striated basal foot and short, non-striated rootlets emanating from the wall of each basal body. The rootlets end in a zone of granules about the proximal region of the basal body, adjacent to which may lie a striated mass of variable shape. All components of the basal body complex of adjacent cilia are independent of each other.

摘要

大鼠脑的纤毛室管膜由一层上皮细胞组成,其腔面反折覆盖在纤毛轴和许多大小不一的突起上。相邻细胞质膜相对较直的外侧部分在离散位点融合,形成五层连接或紧密连接,从而封闭细胞间隙。这些融合通常发生在游离表面下方一定距离处,可独立出现,也可与第二种细胞间连接即黏着小带连续出现。腔面连接通常由黏着小带形成,偶尔也由紧密连接形成。细颗粒状和丝状的细胞质含有核上致密小体,其中一些可能是溶酶体,还有核周细丝的致密螺旋,这些细丝束向外侧质膜延伸。细胞质的顶端区域含有相邻纤毛的基体复合体。这些复合体包括一个横纹状的基足和从每个基体壁发出的短的、无横纹的小根。小根在基体近端区域的颗粒区终止,在其附近可能有一个形状可变的横纹状团块。相邻纤毛基体复合体的所有组成部分相互独立。

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本文引用的文献

1
Intercellular Connection between Smooth Muscle Cells: the Nexus.平滑肌细胞之间的细胞间连接:连接体。
Science. 1962 Aug 31;137(3531):670-2. doi: 10.1126/science.137.3531.670-a.
2
The diaphragm of capillary endothelial fenestrations.毛细血管内皮窗孔的隔膜
J Ultrastruct Res. 1962 Apr;6:171-85. doi: 10.1016/s0022-5320(62)90052-7.
3
Plasma membrane contacts in the central nervous system.中枢神经系统中的质膜接触
J Anat. 1962 Apr;96(Pt 2):237-48.
4
Fixation of neural tissues for electron microscopy by perfusion with solutions of osmium tetroxide.通过用四氧化锇溶液灌注来固定用于电子显微镜检查的神经组织。
J Cell Biol. 1962 Feb;12(2):385-410. doi: 10.1083/jcb.12.2.385.
5
Desmosome development in normal and reassociating cells in the early chick blastoderm.早期鸡胚胚盘正常细胞和重新聚集细胞中的桥粒发育
Dev Biol. 1962 Jun;4:532-48. doi: 10.1016/0012-1606(62)90056-8.
6
Quintuple-layered membrane junctions at terminal bars between endothelial cells.内皮细胞之间终末杆处的五层膜连接。
J Cell Biol. 1962 Feb;12(2):443-8. doi: 10.1083/jcb.12.2.443.
7
Structures corresponding to terminal bars and terminal web in many types of cells.在许多类型细胞中与终末棒和终末网相对应的结构。
Nature. 1960 Jun 4;186:784-8. doi: 10.1038/186784a0.
8
Cell interconnections in normal human cervical epithelium.正常人类宫颈上皮中的细胞连接
J Biophys Biochem Cytol. 1960 Feb;7(1):181-4. doi: 10.1083/jcb.7.1.181.
9
The fine structure of neurons.神经元的精细结构。
J Biophys Biochem Cytol. 1955 Jan;1(1):69-88. doi: 10.1083/jcb.1.1.69.
10
Ependymal cilia: distribution and activity in the adult human brain.室管膜纤毛:在成人大脑中的分布与活性
Science. 1963 Jan 18;139(3551):221-2. doi: 10.1126/science.139.3551.221.