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去铁胺(去铁敏)可提高离体兔心缺氧后恢复过程中心肌组织的氧含量。

Deferoxamine (Desferal) improves the content of oxygen in myocardial tissues during recovery after hypoxia in isolated rabbit heart.

作者信息

Jacobsohn E, Löwe H

机构信息

Institute of Drug Research Berlin.

出版信息

Pharmazie. 1992 May;47(5):381-3.

PMID:1409830
Abstract

On isolated working right heart from rabbit tissue oxygen content as an indicator of function of oxygen transport and storage was observed by moderate hypoxia, hypoxia with deferoxamine (1) and iron infusion. In addition water content of myocardium as an indicator of metabolic damage was evaluated and the copper depletion was established. During the recovery the results presented a beneficial effect on the content of tissue oxygen which is due to 1. But the copper depletion was not changed. Possible connections are discussed.

摘要

在从兔身上分离出的工作右心组织中,以组织氧含量作为氧运输和储存功能的指标,通过中度缺氧、使用去铁胺(1)的缺氧以及铁输注进行观察。此外,评估了心肌含水量作为代谢损伤的指标,并确定了铜缺乏情况。在恢复过程中,结果显示对组织氧含量有有益影响,这归因于1。但铜缺乏情况未改变。讨论了可能的联系。

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1
Deferoxamine (Desferal) improves the content of oxygen in myocardial tissues during recovery after hypoxia in isolated rabbit heart.去铁胺(去铁敏)可提高离体兔心缺氧后恢复过程中心肌组织的氧含量。
Pharmazie. 1992 May;47(5):381-3.
2
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