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[去甲肾上腺素在不同耐缺氧能力大鼠心肌氧化代谢调节中的作用]

[The role of noradrenaline in regulating myocardial oxidative metabolism in rats with different resistances to hypoxia].

作者信息

Luk'ianova L D, Kurlaev S N

出版信息

Biull Eksp Biol Med. 1992 Dec;114(12):586-8.

PMID:1292678
Abstract

The effects of noradrenaline infusion on the regulation of oxidative metabolism in isolated rat heart were studied. It appeared that functional and metabolic parameters of heart of non-resistant and high-resistant to hypoxia rats were different. Noradrenaline changed the balance between aerobic and anaerobic processes in rat heart. It is evident that heart adrenoreceptors are involved in regulation of oxidative metabolism responsible for individual resistance of rat heart to hypoxia.

摘要

研究了去甲肾上腺素输注对离体大鼠心脏氧化代谢调节的影响。结果表明,对缺氧不敏感和高度敏感大鼠心脏的功能和代谢参数有所不同。去甲肾上腺素改变了大鼠心脏有氧和无氧过程之间的平衡。显然,心脏肾上腺素能受体参与了负责大鼠心脏对缺氧个体耐受性的氧化代谢调节。

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